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REVIEW ARTICLE
Year : 2020  |  Volume : 12  |  Issue : 2  |  Page : 106-109

COVID-19: The biology behind the virion


Department of Oral Pathology and Microbiology, SRM Dental College, Chennai, Tamil Nadu, India

Correspondence Address:
V Vasanthi
Department of Oral Pathology and Microbiology, SRM Dental College, Bharathi Salai, Ramapuram, Chennai, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jorr.jorr_12_20

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Coronaviruses are positive-sense RNA viruses with crown-like morphology. This family of virus is known to cause outbreak in many species including humans. The pandemic caused by novel coronavirus COVID-19 is reported to have been spread from bats to human. These groups of emerging zoonotic pathogens bind to the host cell through receptor-mediated mechanism. As the viruses lack proper machinery for self-replication, they depend on the host cell for replication. The resulting viremia causes most common clinical symptoms such as fever, cough progressing to shortness of breath. The number of cases reported from COVID-19 is on the rise since diagnosis. The development of drugs and vaccines is under trial for the management of the novel viral infection.


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