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Year : 2020  |  Volume : 12  |  Issue : 2  |  Page : 59-62

Silver-impregnated platelet-rich fibrin as a barrier membrane

1 Department of Periodontology, MGVM K. B. H. Dental College and Hospital, Nashik, Maharashtra, India
2 Vinay Heart Clinic, Nashik, Maharashtra, India
3 Department of Periodontology, Y. M. T. Dental College and Hospital, Navi Mumbai, Maharashtra, India

Correspondence Address:
Dipali Chaudhari
Department of Periodontology, MGVM K. B. H. Dental College and Hospital, Nashik, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jorr.jorr_32_19

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Introduction: Platelet-rich fibrin (PRF) was developed to eliminate xenofactors form of platelet-rich plasma to be used as a source of growth factor for tissue regeneration. PRF has been used as an autologous grafting material because of its ability to accelerate physiologic wound healing and new bone formation. Aim: To compare mechanical and histologic characteristics of the PRF membrane and silver-impregnated PRF. Materials and Methods: Venous blood was taken from the subjects for PRF preparation. Then, 2 normal PRFs were prepared, and for silver-impregnated PRF, 9 ml of blood in addition to 1 ml of silver nanoparticle suspension was poured into another tube and gently shook with hand to achieve a uniform 1% concentration. The tubes were centrifuged at 3000 rpm for 10 min. The tensile test was done by the universal testing machine:
  1. The remaining pieces of the membranes were fixed in 10% formalin for 24 h to be subjected to hematoxylin and eosin staining and evaluated with the light microscope
  2. Degradation time.
Results: Silver-impregnated showed improved mechanical properties and dense fibrin network than PRF. Conclusion: Silver-impregnated PRF membrane demonstrated properties to be used as a barrier membrane for periodontal reconstruction.

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